跨集群搜索cross cluster search connect_exception

es版本6.2.4
es配置
search:
    remote:
        cluster_one:
            seeds: 181.222.47.8:19220   #由于跨机房，此处配置的是公网ip
启动es日志报错：

[2020-03-03T10:58:29,629][WARN ][o.e.t.RemoteClusterService] [cross] failed to update seed list for cluster: cluster_one
org.elasticsearch.transport.ConnectTransportException: [one-es-logplat06-100101.com][172.16.100.101:19220] connect_exception
at org.elasticsearch.transport.TcpChannel.awaitConnected(TcpChannel.java:165) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.TcpTransport.openConnection(TcpTransport.java:616) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.TcpTransport.connectToNode(TcpTransport.java:513) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.TransportService.connectToNode(TransportService.java:331) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.RemoteClusterConnection$ConnectHandler.lambda$collectRemoteNodes$2(RemoteClusterConnection.java:441) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.common.util.CancellableThreads.executeIO(CancellableThreads.java:105) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.RemoteClusterConnection$ConnectHandler.collectRemoteNodes(RemoteClusterConnection.java:425) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.RemoteClusterConnection$ConnectHandler$1.doRun(RemoteClusterConnection.java:412) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.common.util.concurrent.AbstractRunnable.run(AbstractRunnable.java:37) [elasticsearch-6.2.4.jar:6.2.4]
at java.util.concurrent.Executors$RunnableAdapter.call(Executors.java:511) [?:1.8.0_202]
at java.util.concurrent.FutureTask.run(FutureTask.java:266) [?:1.8.0_202]
at org.elasticsearch.common.util.concurrent.ThreadContext$ContextPreservingRunnable.run(ThreadContext.java:573) [elasticsearch-6.2.4.jar:6.2.4]
at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149) [?:1.8.0_202]
at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624) [?:1.8.0_202]
at java.lang.Thread.run(Thread.java:748) [?:1.8.0_202]
Caused by: io.netty.channel.AbstractChannel$AnnotatedNoRouteToHostException: No route to host: 172.16.100.101/172.16.100.101:19220
at sun.nio.ch.SocketChannelImpl.checkConnect(Native Method) ~[?:?]
at sun.nio.ch.SocketChannelImpl.finishConnect(SocketChannelImpl.java:717) ~[?:?]
at io.netty.channel.socket.nio.NioSocketChannel.doFinishConnect(NioSocketChannel.java:323) ~[?:?]
at io.netty.channel.nio.AbstractNioChannel$AbstractNioUnsafe.finishConnect(AbstractNioChannel.java:340) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKey(NioEventLoop.java:633) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKeysPlain(NioEventLoop.java:545) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKeys(NioEventLoop.java:499) ~[?:?]
at io.netty.channel.nio.NioEventLoop.run(NioEventLoop.java:459) ~[?:?]
at io.netty.util.concurrent.SingleThreadEventExecutor$5.run(SingleThreadEventExecutor.java:858) ~[?:?]
... 1 more
Caused by: java.net.NoRouteToHostException: No route to host
at sun.nio.ch.SocketChannelImpl.checkConnect(Native Method) ~[?:?]
at sun.nio.ch.SocketChannelImpl.finishConnect(SocketChannelImpl.java:717) ~[?:?]
at io.netty.channel.socket.nio.NioSocketChannel.doFinishConnect(NioSocketChannel.java:323) ~[?:?]
at io.netty.channel.nio.AbstractNioChannel$AbstractNioUnsafe.finishConnect(AbstractNioChannel.java:340) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKey(NioEventLoop.java:633) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKeysPlain(NioEventLoop.java:545) ~[?:?]
at io.netty.channel.nio.NioEventLoop.processSelectedKeys(NioEventLoop.java:499) ~[?:?]
at io.netty.channel.nio.NioEventLoop.run(NioEventLoop.java:459) ~[?:?]
at io.netty.util.concurrent.SingleThreadEventExecutor$5.run(SingleThreadEventExecutor.java:858) ~[?:?]
... 1 more
[2020-03-03T10:58:29,633][ERROR][o.e.b.Bootstrap          ] [cross] Exception
java.lang.IllegalStateException: failed to connect to remote clusters
at org.elasticsearch.transport.RemoteClusterService.initializeRemoteClusters(RemoteClusterService.java:340) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.transport.TransportService.doStart(TransportService.java:231) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.common.component.AbstractLifecycleComponent.start(AbstractLifecycleComponent.java:66) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.node.Node.start(Node.java:623) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Bootstrap.start(Bootstrap.java:262) ~[elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Bootstrap.init(Bootstrap.java:332) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Elasticsearch.init(Elasticsearch.java:121) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Elasticsearch.execute(Elasticsearch.java:112) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.cli.EnvironmentAwareCommand.execute(EnvironmentAwareCommand.java:86) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.cli.Command.mainWithoutErrorHandling(Command.java:124) [elasticsearch-cli-6.2.4.jar:6.2.4]
at org.elasticsearch.cli.Command.main(Command.java:90) [elasticsearch-cli-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Elasticsearch.main(Elasticsearch.java:92) [elasticsearch-6.2.4.jar:6.2.4]
at org.elasticsearch.bootstrap.Elasticsearch.main(Elasticsearch.java:85) [elasticsearch-6.2.4.jar:6.2.4]

明明远程集群搜索配置的是公网ip,为何es启动时报错是连接到172.16.100.101内网Ip的错误了？